PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21968922-5	2011	The GR has been a particularly useful system for studying hsp90 because the receptor must be bound to hsp90 to have an open ligand binding cleft that is accessible to steroid (3).	Steroids	167-174	heat shock protein 90 alpha family class A member 1	Homo sapiens	58-63	
21968922-7	2011	As found in the endogenous  GR hsp90 heterocomplex, the GR ligand binding cleft is open and capable of binding steroid.	Steroids	111-118	heat shock protein 90 alpha family class A member 1	Homo sapiens	31-36	
21968922-8	2011	If hsp90 dissociates from the GR or if its function is inhibited, the receptor is unable to bind steroid and requires reconstitution of the GR hsp90 heterocomplex before steroid binding activity is restored (4) .	Steroids	170-177	heat shock protein 90 alpha family class A member 1	Homo sapiens	3-8	
21968922-16	2011	This method can be utilized to test the effects of various chaperone cofactors, novel proteins, and experimental hsp90 or GR inhibitors in order to determine their functional significance on hsp90-mediated steroid binding (8-11).	Steroids	206-213	heat shock protein 90 alpha family class A member 1	Homo sapiens	191-196