PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21951103-7	2012	It was found that acrolein-induced IL-8 production was accompanied by increased levels of phosphorylation of Akt and extracellular signal-regulated kinases (ERK1/2) in HPFs, and that melatonin suppressed IL-8 production in HPFs.	Acrolein	18-26	AKT serine/threonine kinase 1	Homo sapiens	109-112	
21951103-8	2012	These results suggest that melatonin suppresses acrolein-induced IL-8 production via ERK1/2 and phosphatidylinositol 3-kinase (PI3K)/Akt signal inhibition in HPFs.	Acrolein	48-56	AKT serine/threonine kinase 1	Homo sapiens	133-136