PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21924076-0 2011 [Effect of atorvastatin on advanced glycation end products induced monocyte chemoattractant protein-1 expression in cultured human endothelial cells]. Atorvastatin 11-23 C-C motif chemokine ligand 2 Homo sapiens 67-101 21924076-1 2011 OBJECTIVE: To investigate the effects of atorvastatin on advanced glycation end products (AGE) induced monocyte chemoattractant protein-1 (MCP-1) expression in human umbilical vein endothelial cells (HUVECs) and whether this effect could be linked to peroxisome proliferator-activated receptor-gamma (PPAR-gamma) and nuclear factor-kappaB (NF-kappaB). Atorvastatin 41-53 C-C motif chemokine ligand 2 Homo sapiens 103-137 21924076-1 2011 OBJECTIVE: To investigate the effects of atorvastatin on advanced glycation end products (AGE) induced monocyte chemoattractant protein-1 (MCP-1) expression in human umbilical vein endothelial cells (HUVECs) and whether this effect could be linked to peroxisome proliferator-activated receptor-gamma (PPAR-gamma) and nuclear factor-kappaB (NF-kappaB). Atorvastatin 41-53 C-C motif chemokine ligand 2 Homo sapiens 139-144 21924076-4 2011 RESULTS: (1) The expression of MCP-1 mRNA was increased in proportion with increasing concentrations of AGEs which could be blocked by atorvastatin in a dose-dependent manner. Atorvastatin 135-147 C-C motif chemokine ligand 2 Homo sapiens 31-36 21924076-7 2011 (4) PPAR-gamma inhibitor antagonized the effect of atorvastatin on the expression of phospho-NF-kappaB p65 protein, nonphospho-NF-kappaB p65 protein and MCP-1 mRNA stimulated by AGE in HUVECs (P < 0.01). Atorvastatin 51-63 C-C motif chemokine ligand 2 Homo sapiens 153-158