PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21870821-3 2011 The aromatase/cyclases (ARO/CYCs) are an important component of the type II polyketide synthase (PKS) and help fold the polyketide for regiospecific cyclizations of the first ring and/or aromatization, promoting two commonly observed first-ring cyclization patterns for the bacterial type II PKSs: C7-C12 and C9-C14. Polyketides 76-86 cytochrome c, somatic Homo sapiens 28-32 21870821-6 2011 In this work, we present the 2.4 A crystal structure of ZhuI, a C7-C12-specific first-ring ARO/CYC from the type II PKS pathway responsible for the production of the R1128 polyketides. Polyketides 172-183 cytochrome c, somatic Homo sapiens 95-98