PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21868758-3 2011 DHEA and androstenedione are synthesized by the adrenals through the sequential actions of the cytochrome P450 enzymes CYP11A1 and CYP17A1, so that CYP17A1 inhibitors such as abiraterone are effective therapies for CRPC. Androstenedione 9-24 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 131-138 21868758-3 2011 DHEA and androstenedione are synthesized by the adrenals through the sequential actions of the cytochrome P450 enzymes CYP11A1 and CYP17A1, so that CYP17A1 inhibitors such as abiraterone are effective therapies for CRPC. Androstenedione 9-24 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 148-155