PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21868755-0 2011 Celecoxib promotes c-FLIP degradation through Akt-independent inhibition of GSK3. Celecoxib 0-9 AKT serine/threonine kinase 1 Homo sapiens 46-49 21868755-5 2011 We found that celecoxib controlled c-FLIP ubiquitination through Akt-independent inhibition of glycogen synthase kinase-3 (GSK3), itself a candidate therapeutic target of interest in colon cancer. Celecoxib 14-23 AKT serine/threonine kinase 1 Homo sapiens 65-68 21868755-6 2011 Celecoxib increased the levels of phosphorylated GSK3, including the alpha and beta forms, even in cell lines, where phosphorylated Akt levels were not increased. Celecoxib 0-9 AKT serine/threonine kinase 1 Homo sapiens 132-135