PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21832094-3	2011	Importantly, desipramine belongs to a group of tricyclic antidepressant compounds that can simultaneously block hERG and inhibit its surface expression.	Desipramine	13-24	ETS transcription factor ERG	Homo sapiens	112-116	
21832094-5	2011	Here, we have studied in detail how desipramine inhibits hERG surface expression.	Desipramine	36-47	ETS transcription factor ERG	Homo sapiens	57-61	
21832094-6	2011	We find a previously unrecognized combination of two entirely different mechanisms; desipramine increases hERG endocytosis and degradation as a consequence of drug-induced channel ubiquitination and simultaneously inhibits hERG forward trafficking from the endoplasmic reticulum.	Desipramine	84-95	ETS transcription factor ERG	Homo sapiens	106-110	
21832094-6	2011	We find a previously unrecognized combination of two entirely different mechanisms; desipramine increases hERG endocytosis and degradation as a consequence of drug-induced channel ubiquitination and simultaneously inhibits hERG forward trafficking from the endoplasmic reticulum.	Desipramine	84-95	ETS transcription factor ERG	Homo sapiens	223-227