PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21680899-5	2011	Furthermore, cilostazol-activated cAMP response element (CRE)-binding protein (CREB), including phosphorylation at Ser133 and its nuclear translocation.	Cilostazol	13-23	cAMP responsive element binding protein 1	Homo sapiens	79-83	
21680899-6	2011	Deletion and mutational analysis of the contractile protein promoters along with chromatin immunoprecipitation using anti-CREB antibody showed that CRE is essential for cilostazol-induced contractile protein expression.	Cilostazol	169-179	cAMP responsive element binding protein 1	Homo sapiens	122-126	
21680899-7	2011	Transfection of dominant-negative CREB (mutated Ser133) plasmid in VSMCs blocked cilostazol-stimulated contractile protein expression.	Cilostazol	81-91	cAMP responsive element binding protein 1	Homo sapiens	34-38	
21680899-8	2011	In vivo, cilostazol upregulated contractile proteins and induced the activation of CREB in the neointima of balloon-injured arteries.	Cilostazol	9-19	cAMP responsive element binding protein 1	Homo sapiens	83-87	
21680899-9	2011	CONCLUSIONS: Cilostazol promotes VSMC differentiation through the cAMP/PKA/CREB signaling cascade.	Cilostazol	13-23	cAMP responsive element binding protein 1	Homo sapiens	75-79