PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21660448-0	2012	5, 7-Dimethoxyflavone sensitizes TRAIL-induced apoptosis through DR5 upregulation in hepatocellular carcinoma cells.	5,7-dimethoxyflavone	0-21	TNF superfamily member 10	Homo sapiens	33-38	
21660448-0	2012	5, 7-Dimethoxyflavone sensitizes TRAIL-induced apoptosis through DR5 upregulation in hepatocellular carcinoma cells.	5,7-dimethoxyflavone	0-21	TNF receptor superfamily member 10b	Homo sapiens	65-68	
21660448-2	2012	The aim of this study was to examine whether DMF sensitizes human hepatocellular carcinoma (HCC) cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis and its mechanism.	Dimethylformamide	45-48	TNF superfamily member 10	Homo sapiens	106-161	
21660448-2	2012	The aim of this study was to examine whether DMF sensitizes human hepatocellular carcinoma (HCC) cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis and its mechanism.	Dimethylformamide	45-48	TNF superfamily member 10	Homo sapiens	163-168	
21660448-8	2012	RESULTS: Our results demonstrated subtoxic concentrations of DMF sensitize HCC cells to TRAIL-induced apoptosis and induce the death receptor 5 (DR5) expression level, accompanying the generation of reactive oxygen species (ROS) and the upregulation of CHOP, GPR78, and ATF4 protein expression.	Dimethylformamide	61-64	TNF superfamily member 10	Homo sapiens	88-93	
21660448-8	2012	RESULTS: Our results demonstrated subtoxic concentrations of DMF sensitize HCC cells to TRAIL-induced apoptosis and induce the death receptor 5 (DR5) expression level, accompanying the generation of reactive oxygen species (ROS) and the upregulation of CHOP, GPR78, and ATF4 protein expression.	Dimethylformamide	61-64	TNF receptor superfamily member 10b	Homo sapiens	127-143	
21660448-8	2012	RESULTS: Our results demonstrated subtoxic concentrations of DMF sensitize HCC cells to TRAIL-induced apoptosis and induce the death receptor 5 (DR5) expression level, accompanying the generation of reactive oxygen species (ROS) and the upregulation of CHOP, GPR78, and ATF4 protein expression.	Dimethylformamide	61-64	TNF receptor superfamily member 10b	Homo sapiens	145-148	
21660448-8	2012	RESULTS: Our results demonstrated subtoxic concentrations of DMF sensitize HCC cells to TRAIL-induced apoptosis and induce the death receptor 5 (DR5) expression level, accompanying the generation of reactive oxygen species (ROS) and the upregulation of CHOP, GPR78, and ATF4 protein expression.	Dimethylformamide	61-64	DNA damage inducible transcript 3	Homo sapiens	253-257	
21660448-8	2012	RESULTS: Our results demonstrated subtoxic concentrations of DMF sensitize HCC cells to TRAIL-induced apoptosis and induce the death receptor 5 (DR5) expression level, accompanying the generation of reactive oxygen species (ROS) and the upregulation of CHOP, GPR78, and ATF4 protein expression.	Dimethylformamide	61-64	G protein-coupled receptor 78	Homo sapiens	259-264	
21660448-8	2012	RESULTS: Our results demonstrated subtoxic concentrations of DMF sensitize HCC cells to TRAIL-induced apoptosis and induce the death receptor 5 (DR5) expression level, accompanying the generation of reactive oxygen species (ROS) and the upregulation of CHOP, GPR78, and ATF4 protein expression.	Dimethylformamide	61-64	activating transcription factor 4	Homo sapiens	270-274	
21660448-9	2012	Pretreatment with N-acetylcysteine (NAC) inhibited DMF-induced upregulation of DR5, CHOP, GPR78, and ATF4 protein expression and blocked the cotreatment-induced apoptosis.	Acetylcysteine	18-34	TNF receptor superfamily member 10b	Homo sapiens	79-82	
21660448-9	2012	Pretreatment with N-acetylcysteine (NAC) inhibited DMF-induced upregulation of DR5, CHOP, GPR78, and ATF4 protein expression and blocked the cotreatment-induced apoptosis.	Acetylcysteine	18-34	DNA damage inducible transcript 3	Homo sapiens	84-88	
21660448-9	2012	Pretreatment with N-acetylcysteine (NAC) inhibited DMF-induced upregulation of DR5, CHOP, GPR78, and ATF4 protein expression and blocked the cotreatment-induced apoptosis.	Acetylcysteine	18-34	G protein-coupled receptor 78	Homo sapiens	90-95	
21660448-9	2012	Pretreatment with N-acetylcysteine (NAC) inhibited DMF-induced upregulation of DR5, CHOP, GPR78, and ATF4 protein expression and blocked the cotreatment-induced apoptosis.	Acetylcysteine	18-34	activating transcription factor 4	Homo sapiens	101-105	
21660448-9	2012	Pretreatment with N-acetylcysteine (NAC) inhibited DMF-induced upregulation of DR5, CHOP, GPR78, and ATF4 protein expression and blocked the cotreatment-induced apoptosis.	Acetylcysteine	36-39	TNF receptor superfamily member 10b	Homo sapiens	79-82	
21660448-9	2012	Pretreatment with N-acetylcysteine (NAC) inhibited DMF-induced upregulation of DR5, CHOP, GPR78, and ATF4 protein expression and blocked the cotreatment-induced apoptosis.	Acetylcysteine	36-39	DNA damage inducible transcript 3	Homo sapiens	84-88	
21660448-9	2012	Pretreatment with N-acetylcysteine (NAC) inhibited DMF-induced upregulation of DR5, CHOP, GPR78, and ATF4 protein expression and blocked the cotreatment-induced apoptosis.	Acetylcysteine	36-39	G protein-coupled receptor 78	Homo sapiens	90-95	
21660448-9	2012	Pretreatment with N-acetylcysteine (NAC) inhibited DMF-induced upregulation of DR5, CHOP, GPR78, and ATF4 protein expression and blocked the cotreatment-induced apoptosis.	Acetylcysteine	36-39	activating transcription factor 4	Homo sapiens	101-105	
21660448-9	2012	Pretreatment with N-acetylcysteine (NAC) inhibited DMF-induced upregulation of DR5, CHOP, GPR78, and ATF4 protein expression and blocked the cotreatment-induced apoptosis.	Dimethylformamide	51-54	TNF receptor superfamily member 10b	Homo sapiens	79-82	
21660448-9	2012	Pretreatment with N-acetylcysteine (NAC) inhibited DMF-induced upregulation of DR5, CHOP, GPR78, and ATF4 protein expression and blocked the cotreatment-induced apoptosis.	Dimethylformamide	51-54	DNA damage inducible transcript 3	Homo sapiens	84-88	
21660448-9	2012	Pretreatment with N-acetylcysteine (NAC) inhibited DMF-induced upregulation of DR5, CHOP, GPR78, and ATF4 protein expression and blocked the cotreatment-induced apoptosis.	Dimethylformamide	51-54	G protein-coupled receptor 78	Homo sapiens	90-95	
21660448-9	2012	Pretreatment with N-acetylcysteine (NAC) inhibited DMF-induced upregulation of DR5, CHOP, GPR78, and ATF4 protein expression and blocked the cotreatment-induced apoptosis.	Dimethylformamide	51-54	activating transcription factor 4	Homo sapiens	101-105	
21660448-10	2012	Furthermore, DMF-mediated sensitization of HCC cells to TRAIL was reduced by administration of a blocking antibody or small interfering RNAs for DR5, salubrinal, an inhibitor of ER stress, and the small interfering RNAs for CHOP.	Dimethylformamide	13-16	TNF superfamily member 10	Homo sapiens	56-61	
21660448-10	2012	Furthermore, DMF-mediated sensitization of HCC cells to TRAIL was reduced by administration of a blocking antibody or small interfering RNAs for DR5, salubrinal, an inhibitor of ER stress, and the small interfering RNAs for CHOP.	Dimethylformamide	13-16	TNF receptor superfamily member 10b	Homo sapiens	145-148	
21660448-10	2012	Furthermore, DMF-mediated sensitization of HCC cells to TRAIL was reduced by administration of a blocking antibody or small interfering RNAs for DR5, salubrinal, an inhibitor of ER stress, and the small interfering RNAs for CHOP.	Dimethylformamide	13-16	DNA damage inducible transcript 3	Homo sapiens	224-228	
21660448-10	2012	Furthermore, DMF-mediated sensitization of HCC cells to TRAIL was reduced by administration of a blocking antibody or small interfering RNAs for DR5, salubrinal, an inhibitor of ER stress, and the small interfering RNAs for CHOP.	salubrinal	150-160	TNF superfamily member 10	Homo sapiens	56-61	
21660448-12	2012	CONCLUSION: The present study demonstrates that DMF selectively enhances TRAIL-induced apoptosis by ROS-stimulated ER-stress triggering CHOP-mediated DR5 upregulation in HCC.	Dimethylformamide	48-51	TNF superfamily member 10	Homo sapiens	73-78	
21660448-12	2012	CONCLUSION: The present study demonstrates that DMF selectively enhances TRAIL-induced apoptosis by ROS-stimulated ER-stress triggering CHOP-mediated DR5 upregulation in HCC.	Dimethylformamide	48-51	DNA damage inducible transcript 3	Homo sapiens	136-140	
21660448-12	2012	CONCLUSION: The present study demonstrates that DMF selectively enhances TRAIL-induced apoptosis by ROS-stimulated ER-stress triggering CHOP-mediated DR5 upregulation in HCC.	Dimethylformamide	48-51	TNF receptor superfamily member 10b	Homo sapiens	150-153	
21660448-12	2012	CONCLUSION: The present study demonstrates that DMF selectively enhances TRAIL-induced apoptosis by ROS-stimulated ER-stress triggering CHOP-mediated DR5 upregulation in HCC.	Reactive Oxygen Species	100-103	TNF superfamily member 10	Homo sapiens	73-78	
21660448-12	2012	CONCLUSION: The present study demonstrates that DMF selectively enhances TRAIL-induced apoptosis by ROS-stimulated ER-stress triggering CHOP-mediated DR5 upregulation in HCC.	Reactive Oxygen Species	100-103	DNA damage inducible transcript 3	Homo sapiens	136-140	
21660448-12	2012	CONCLUSION: The present study demonstrates that DMF selectively enhances TRAIL-induced apoptosis by ROS-stimulated ER-stress triggering CHOP-mediated DR5 upregulation in HCC.	Reactive Oxygen Species	100-103	TNF receptor superfamily member 10b	Homo sapiens	150-153