PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21586598-3	2012	The aim of this study was to develop biodegradable, tetracycline-loaded microparticles made of two polymers: PLGA and zein which were compressed into monolithic devices.	Tetracycline	52-64	zein	Zea mays	118-122	
21586598-5	2012	The interaction of tetracycline with the corn protein zein was studied by nuclear magnetic resonance (NMR), Fourier transform infrared, and X-ray diffraction.	Tetracycline	19-31	zein	Zea mays	54-58	
21586598-6	2012	The hydrophobic interaction of tetracycline with zein in the formulations was deduced from the NMR studies, whereas X-ray diffraction studies showed a new crystalline state of the drug in the presence of the protein.	Tetracycline	31-43	zein	Zea mays	49-53	
21586598-8	2012	Sustained release of tetracycline was obtained, and the proportion of zein in the inserts had a great impact on the drug release.	Tetracycline	21-33	zein	Zea mays	70-74	
21586598-10	2012	In conclusion, the PLGA:zein delivery system described in this study was found to be effective in controlled delivery of tetracycline, and hence may be suitable for intra-pocket delivery of antimicrobial agents in the treatment of periodontitis.	Tetracycline	121-133	zein	Zea mays	24-28