PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21528155-0 2011 All-trans retinoic acid upregulates reduced CD38 transcription in lymphoblastoid cell lines from Autism spectrum disorder. Tretinoin 10-23 CD38 molecule Homo sapiens 44-48 21528155-5 2011 One of these, all-trans retinoic acid (ATRA), a known inducer of CD38, was added during cell culture and tested on a large sample of N = 120 lymphoblastoid cell (LBC) lines from ASD patients and their parents. Tretinoin 14-37 CD38 molecule Homo sapiens 65-69 21528155-5 2011 One of these, all-trans retinoic acid (ATRA), a known inducer of CD38, was added during cell culture and tested on a large sample of N = 120 lymphoblastoid cell (LBC) lines from ASD patients and their parents. Tretinoin 39-43 CD38 molecule Homo sapiens 65-69 21528155-6 2011 Analysis of CD38 mRNA levels shows that ATRA has an upmodulatory potential on LBC derived from ASD patients as well as from their parents. Tretinoin 40-44 CD38 molecule Homo sapiens 12-16 21528155-9 2011 In addition, analysis of the role of genetic polymorphisms in the dynamics of the molecule revealed that the genotype of a single-nucleotide polymorphism (rs6449182; C>G variation) in the CpG island of intron 1, harboring the retinoic-acid response element, exerts differential roles in CD38 expression in ASD and in parental LBC. Tretinoin 229-242 CD38 molecule Homo sapiens 290-294