PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21519916-4	2011	Concomitantly, the co-treatment of cryptotanshinone and TNF-alpha elicited apoptosis, manifested by enhanced the number of terminal deoxynucleotide transferase-mediated dUTP-nick-end labeling (TUNEL)-positive cells, the sub-G1 cell populations, and the activation of caspase-8 and -3, in comparison with the treatment with either drug alone.	cryptotanshinone	35-51	caspase 8	Homo sapiens	267-283	
21519916-5	2011	The treatment with cryptotanshinone further suppressed TNF-alpha-mediated expression of c-FLIP(L), Bcl-x(L), but the increased level of tBid (a caspase-8 substrate).	cryptotanshinone	19-35	caspase 8	Homo sapiens	144-153	
21519916-10	2011	Overall, our findings suggest that cryptotanshinone can sensitize TNF-alpha-induced apoptosis in human myeloid leukemia KBM-5 cells, which appears through ROS-dependent activation of caspase-8 and p38.	cryptotanshinone	35-51	caspase 8	Homo sapiens	183-192