PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21484577-4 2011 In addition, it is now demonstrated that AMPK is one of the probable (albeit indirect) targets of major antidiabetic drugs drugs including the biguanides (metformin metformin ) and thiazolidinedione thiazolidinedione s, as well as of insulin-sensitizing adipokines (e.g., adiponectin adiponectin ). Biguanides 143-153 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 41-45