PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2148087-0	1990	Enhancement of bradykinin-induced prostacyclin synthesis in porcine aortic endothelial cells by pertussis toxin.	Epoprostenol	34-46	kininogen 1	Homo sapiens	15-25	
2148087-2	1990	Bradykinin-stimulated prostacyclin synthesis in porcine aortic endothelial cells was enhanced by pretreatment of the cells with pertussis toxin or islet-activating protein (IAP) for 5 hr or longer.	Epoprostenol	22-34	kininogen 1	Homo sapiens	0-10	
2148087-2	1990	Bradykinin-stimulated prostacyclin synthesis in porcine aortic endothelial cells was enhanced by pretreatment of the cells with pertussis toxin or islet-activating protein (IAP) for 5 hr or longer.	Epoprostenol	22-34	islet amyloid polypeptide	Homo sapiens	147-171	
2148087-2	1990	Bradykinin-stimulated prostacyclin synthesis in porcine aortic endothelial cells was enhanced by pretreatment of the cells with pertussis toxin or islet-activating protein (IAP) for 5 hr or longer.	Epoprostenol	22-34	islet amyloid polypeptide	Homo sapiens	173-176	
2148087-3	1990	Although ADP-ribosylation of a protein with a molecular weight of 41-42 kD in the cell membranes was completed by 3 hr after the addition of IAP into the incubation medium, there was good correlation between enhancement of bradykinin-induced prostacyclin synthesis and ADP-ribosylation of the IAP substrate over a wide range of IAP concentrations.	Epoprostenol	242-254	islet amyloid polypeptide	Homo sapiens	141-144	
2148087-3	1990	Although ADP-ribosylation of a protein with a molecular weight of 41-42 kD in the cell membranes was completed by 3 hr after the addition of IAP into the incubation medium, there was good correlation between enhancement of bradykinin-induced prostacyclin synthesis and ADP-ribosylation of the IAP substrate over a wide range of IAP concentrations.	Epoprostenol	242-254	kininogen 1	Homo sapiens	223-233	
2148087-4	1990	Furthermore, even if IAP was removed from the incubation medium at 3 hr, bradykinin-induced prostaglandin synthesis at 24 hr was still potentiated.	Prostaglandins	92-105	islet amyloid polypeptide	Homo sapiens	21-24	
2148087-4	1990	Furthermore, even if IAP was removed from the incubation medium at 3 hr, bradykinin-induced prostaglandin synthesis at 24 hr was still potentiated.	Prostaglandins	92-105	kininogen 1	Homo sapiens	73-83	
2148087-5	1990	Cycloheximide and actinomycin D enhanced bradykinin-induced prostacyclin synthesis and apparently blocked the effect of IAP.	Cycloheximide	0-13	kininogen 1	Homo sapiens	41-51	
2148087-5	1990	Cycloheximide and actinomycin D enhanced bradykinin-induced prostacyclin synthesis and apparently blocked the effect of IAP.	Cycloheximide	0-13	islet amyloid polypeptide	Homo sapiens	120-123	
2148087-5	1990	Cycloheximide and actinomycin D enhanced bradykinin-induced prostacyclin synthesis and apparently blocked the effect of IAP.	Dactinomycin	18-31	kininogen 1	Homo sapiens	41-51	
2148087-5	1990	Cycloheximide and actinomycin D enhanced bradykinin-induced prostacyclin synthesis and apparently blocked the effect of IAP.	Dactinomycin	18-31	islet amyloid polypeptide	Homo sapiens	120-123	
2148087-5	1990	Cycloheximide and actinomycin D enhanced bradykinin-induced prostacyclin synthesis and apparently blocked the effect of IAP.	Epoprostenol	60-72	kininogen 1	Homo sapiens	41-51	
2148087-6	1990	Since this result suggested the involvement of an inhibitor protein(s) of prostacyclin synthesis in the IAP effect, we studied the effect of IAP on the level of lipocortin I which is known to inhibit phospholipase A2.	Epoprostenol	74-86	islet amyloid polypeptide	Homo sapiens	104-107	
2148087-8	1990	These results suggest that the enhancement of bradykinin-induced prostacyclin synthesis by IAP is associated with a decrease in the level of lipocortin I.	Epoprostenol	65-77	kininogen 1	Homo sapiens	46-56	
2148087-8	1990	These results suggest that the enhancement of bradykinin-induced prostacyclin synthesis by IAP is associated with a decrease in the level of lipocortin I.	Epoprostenol	65-77	islet amyloid polypeptide	Homo sapiens	91-94