PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21454712-0	2011	Noxa/Bcl-2 protein interactions contribute to bortezomib resistance in human lymphoid cells.	Bortezomib	46-56	BCL2 apoptosis regulator	Homo sapiens	5-10	
21454712-7	2011	When killing by bortezomib (an agent whose cytotoxicity in Jurkat T-cell leukemia cells is dependent on Noxa) was examined, apoptosis was enhanced by the Bcl-2/Bcl-x(L) antagonist ABT-737 or by Bcl-2 down-regulation and diminished by Bcl-2 overexpression.	Bortezomib	16-26	BCL2 apoptosis regulator	Homo sapiens	154-159	
21454712-8	2011	Collectively, these observations not only establish the ability of Noxa and Bcl-2 to interact but also identify Bcl-2 overexpression as a potential mechanism of bortezomib resistance.	Bortezomib	161-171	BCL2 apoptosis regulator	Homo sapiens	112-117