PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21427706-3 2011 We hypothesized that JX-594 and sorafenib, a small molecule inhibitor of B-raf and vascular endothelial growth factor receptor (VEGFR) approved for HCC, would have clinical benefit in combination given their demonstrated efficacy in HCC patients and their complementary mechanisms-of-action. Sorafenib 32-41 B-Raf proto-oncogene, serine/threonine kinase Homo sapiens 73-78