PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21389782-0	2011	Potent genistein derivatives as inhibitors of estrogen receptor alpha-positive breast cancer.	Genistein	7-16	estrogen receptor 1	Homo sapiens	46-69	
21389782-5	2011	In our analysis, we noticed that at IC(50) concentrations, the MA-6, MA-8 and MA-19 Genistein derivatives induced apoptosis, inhibited ER-alpha messenger RNA expression and increased the ratio of ER-beta to ER-alpha levels in a manner comparable to the parent compound Genistein.	Genistein	84-93	estrogen receptor 1	Homo sapiens	135-143	
21389782-5	2011	In our analysis, we noticed that at IC(50) concentrations, the MA-6, MA-8 and MA-19 Genistein derivatives induced apoptosis, inhibited ER-alpha messenger RNA expression and increased the ratio of ER-beta to ER-alpha levels in a manner comparable to the parent compound Genistein.	Genistein	84-93	estrogen receptor 1	Homo sapiens	207-215	
21389782-6	2011	Of note, these three modified Genistein derivatives exerted their effects at concentrations 10-15 times lower than the parent compound, decreasing the likelihood of significant ER- alpha pathway activation, which has been a concern for Genistein.	Genistein	30-39	estrogen receptor 1	Homo sapiens	177-186	
21389782-6	2011	Of note, these three modified Genistein derivatives exerted their effects at concentrations 10-15 times lower than the parent compound, decreasing the likelihood of significant ER- alpha pathway activation, which has been a concern for Genistein.	Genistein	236-245	estrogen receptor 1	Homo sapiens	177-186