PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21387786-2 2010 The therapeutic action of RIS depends not only on the parent compound but also its major active metabolite, 9-hydroxyrisperidone (9-OH-RIS), and the pharmacokinetics is modified by the genetic polymorphism of CYP2D6, the main site o RIS metabolism. Paliperidone Palmitate 108-128 cytochrome P450 family 2 subfamily D member 6 Homo sapiens 209-215 21387786-2 2010 The therapeutic action of RIS depends not only on the parent compound but also its major active metabolite, 9-hydroxyrisperidone (9-OH-RIS), and the pharmacokinetics is modified by the genetic polymorphism of CYP2D6, the main site o RIS metabolism. Paliperidone Palmitate 130-138 cytochrome P450 family 2 subfamily D member 6 Homo sapiens 209-215