PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21355834-2 2011 Phosphodiesterase 10A (PDE10A) is a basal ganglia specific hydrolase, which plays an essential role in regulating cAMP/PKA and cGMP/PKG signalling cascades by controlling the magnitude, duration and cellular location of cAMP/cGMP elevation. Cyclic AMP 114-118 phosphodiesterase 10A Homo sapiens 0-21 21355834-2 2011 Phosphodiesterase 10A (PDE10A) is a basal ganglia specific hydrolase, which plays an essential role in regulating cAMP/PKA and cGMP/PKG signalling cascades by controlling the magnitude, duration and cellular location of cAMP/cGMP elevation. Cyclic AMP 114-118 phosphodiesterase 10A Homo sapiens 23-29 21355834-2 2011 Phosphodiesterase 10A (PDE10A) is a basal ganglia specific hydrolase, which plays an essential role in regulating cAMP/PKA and cGMP/PKG signalling cascades by controlling the magnitude, duration and cellular location of cAMP/cGMP elevation. Cyclic AMP 220-224 phosphodiesterase 10A Homo sapiens 0-21 21355834-2 2011 Phosphodiesterase 10A (PDE10A) is a basal ganglia specific hydrolase, which plays an essential role in regulating cAMP/PKA and cGMP/PKG signalling cascades by controlling the magnitude, duration and cellular location of cAMP/cGMP elevation. Cyclic AMP 220-224 phosphodiesterase 10A Homo sapiens 23-29 21355834-3 2011 Biochemical and behavioral data indicate that PDE10A inhibition activates cAMP/PKA signalling in the basal ganglia, leading to the potentiation of dopamine D1 receptor signalling, and concomitant inhibition of dopamine D2 receptor signalling. Cyclic AMP 74-78 phosphodiesterase 10A Homo sapiens 46-52