PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21346370-0 2011 Possible association of SLC22A2 polymorphisms with aspirin-intolerant asthma. Aspirin 51-58 solute carrier family 22 member 2 Homo sapiens 24-31 21346370-2 2011 Solute carrier family 22, member 2 (SLC22A2), also known as organic cation transporter 2 (OCT2), is predominantly expressed in the luminal membrane of airway epithelial cells and has been shown to mediate the transport of prostaglandins on the cyclooxygenase pathway which is regulated by aspirin blockage. Aspirin 289-296 solute carrier family 22 member 2 Homo sapiens 0-34 21346370-2 2011 Solute carrier family 22, member 2 (SLC22A2), also known as organic cation transporter 2 (OCT2), is predominantly expressed in the luminal membrane of airway epithelial cells and has been shown to mediate the transport of prostaglandins on the cyclooxygenase pathway which is regulated by aspirin blockage. Aspirin 289-296 solute carrier family 22 member 2 Homo sapiens 36-43 21346370-2 2011 Solute carrier family 22, member 2 (SLC22A2), also known as organic cation transporter 2 (OCT2), is predominantly expressed in the luminal membrane of airway epithelial cells and has been shown to mediate the transport of prostaglandins on the cyclooxygenase pathway which is regulated by aspirin blockage. Aspirin 289-296 solute carrier family 22 member 2 Homo sapiens 60-88 21346370-2 2011 Solute carrier family 22, member 2 (SLC22A2), also known as organic cation transporter 2 (OCT2), is predominantly expressed in the luminal membrane of airway epithelial cells and has been shown to mediate the transport of prostaglandins on the cyclooxygenase pathway which is regulated by aspirin blockage. Aspirin 289-296 solute carrier family 22 member 2 Homo sapiens 90-94 21346370-4 2011 METHODS: To investigate the associations between AIA and genetic polymorphisms of the SLC22A2 gene, 18 variants were genotyped in 163 AIA subjects and 429 aspirin-tolerant asthma (ATA) controls. Aspirin 155-162 solute carrier family 22 member 2 Homo sapiens 86-93 21346370-8 2011 In addition, a polymorphism in intron 4 (rs3912161) and a haplotype (SLC22A2-ht3) showed significantly stronger association signals with the FEV(1) fall rate induced by aspirin provocation in AIA subjects compared with ATA controls (p = 0.004, P(corr) = 0.05). Aspirin 169-176 solute carrier family 22 member 2 Homo sapiens 69-76 21346370-9 2011 CONCLUSION: Our findings suggest that SLC22A2 could be a susceptibility gene for aspirin intolerance in asthmatics. Aspirin 81-88 solute carrier family 22 member 2 Homo sapiens 38-45