PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21327909-0 2011 Effects of SLCO1B1 polymorphisms on the pharmacokinetics and pharmacodynamics of repaglinide in healthy Chinese volunteers. repaglinide 81-92 solute carrier organic anion transporter family member 1B1 Homo sapiens 11-18 21327909-2 2011 The objective of this research was to study the effects of SLCO1B1 polymorphisms on the pharmacokinetics and pharmacodynamics of repaglinide in healthy Chinese volunteers. repaglinide 129-140 solute carrier organic anion transporter family member 1B1 Homo sapiens 59-66 21327909-9 2011 CONCLUSIONS: SLCO1B1*1B/*1B genotype is associated with reduced pharmacokinetic exposure after a single dose oral administration of 2 mg repaglinide, including decreased AUC(0- ) and increased clearance of repaglinide. repaglinide 137-148 solute carrier organic anion transporter family member 1B1 Homo sapiens 13-20 21327909-9 2011 CONCLUSIONS: SLCO1B1*1B/*1B genotype is associated with reduced pharmacokinetic exposure after a single dose oral administration of 2 mg repaglinide, including decreased AUC(0- ) and increased clearance of repaglinide. repaglinide 206-217 solute carrier organic anion transporter family member 1B1 Homo sapiens 13-20 21327909-10 2011 Moreover, this polymorphism of SLCO1B1 has significant influence on the pharmacokinetics of repaglinide, but no effects on its pharmacodynamics. repaglinide 92-103 solute carrier organic anion transporter family member 1B1 Homo sapiens 31-38