PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21291942-0 2011 Targeting oxidative stress, mitochondrial dysfunction and neuroinflammatory signaling by selective cyclooxygenase (COX)-2 inhibitors mitigates MPTP-induced neurotoxicity in mice. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 143-147 cytochrome c oxidase II, mitochondrial Mus musculus 99-121 21291942-2 2011 The present study was focused on the possible neuroprotective effect of selective cyclooxygenase (COX)-2-inhibitors: valdecoxib and NS-398 in 1-methyl-4-phenyl-1,2,3,6-tertahydropyridine (MPTP)-induced neurotoxicity in mice. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 188-192 cytochrome c oxidase II, mitochondrial Mus musculus 82-104 21291942-9 2011 The findings of the present study substantiate the neuroprotective role of selective COX-2 inhibitors in ameliorating MPTP-induced neurodegeneration in mice and suggest the possible therapeutic potential of these drugs in the management of PD. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 118-122 cytochrome c oxidase II, mitochondrial Mus musculus 85-90