PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21232776-0	2011	RNAi-mediated down-regulation of ornithine decarboxylase (ODC) leads to reduced nicotine and increased anatabine levels in transgenic Nicotiana tabacum L. In leaf and root tissues of Nicotiana tabacum L. (common tobacco), nicotine is by far the predominant pyridine alkaloid, with anatabine representing only a minor component of the total alkaloid fraction.	Nicotine	80-88	ornithine decarboxylase	Nicotiana tabacum	33-56	
21232776-0	2011	RNAi-mediated down-regulation of ornithine decarboxylase (ODC) leads to reduced nicotine and increased anatabine levels in transgenic Nicotiana tabacum L. In leaf and root tissues of Nicotiana tabacum L. (common tobacco), nicotine is by far the predominant pyridine alkaloid, with anatabine representing only a minor component of the total alkaloid fraction.	Nicotine	80-88	ornithine decarboxylase	Nicotiana tabacum	58-61	
21232776-0	2011	RNAi-mediated down-regulation of ornithine decarboxylase (ODC) leads to reduced nicotine and increased anatabine levels in transgenic Nicotiana tabacum L. In leaf and root tissues of Nicotiana tabacum L. (common tobacco), nicotine is by far the predominant pyridine alkaloid, with anatabine representing only a minor component of the total alkaloid fraction.	Nicotine	222-230	ornithine decarboxylase	Nicotiana tabacum	33-56	
21232776-0	2011	RNAi-mediated down-regulation of ornithine decarboxylase (ODC) leads to reduced nicotine and increased anatabine levels in transgenic Nicotiana tabacum L. In leaf and root tissues of Nicotiana tabacum L. (common tobacco), nicotine is by far the predominant pyridine alkaloid, with anatabine representing only a minor component of the total alkaloid fraction.	Nicotine	222-230	ornithine decarboxylase	Nicotiana tabacum	58-61	
21232776-1	2011	The pyrrolidine ring of nicotine is derived from the diamine putrescine, which can be synthesized either directly from ornithine via the action of ODC, or from arginine via a three enzymatic step process, initiated by ADC.	Nicotine	24-32	ornithine decarboxylase	Nicotiana tabacum	147-150	
21232776-4	2011	We observed a marked effect upon the alkaloid profile of transgenic tissues, with ODC transcript down-regulation leading to reduced nicotine and increased anatabine levels in both cultured hairy roots and intact greenhouse-grown plants.	Nicotine	132-140	ornithine decarboxylase	Nicotiana tabacum	82-85	
21232776-6	2011	We conclude that the ODC mediated route to putrescine plays an important role in determining the normal nicotine:anatabine profile in N. tabacum and is essential in allowing N. tabacum to increase nicotine levels in response to wound-associated stress.	Nicotine	104-112	ornithine decarboxylase	Nicotiana tabacum	21-24	
21232776-6	2011	We conclude that the ODC mediated route to putrescine plays an important role in determining the normal nicotine:anatabine profile in N. tabacum and is essential in allowing N. tabacum to increase nicotine levels in response to wound-associated stress.	Nicotine	197-205	ornithine decarboxylase	Nicotiana tabacum	21-24