PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2104895-2 1990 This study was designed to simulate purine nucleoside phosphorylase (PNP) deficiency by preincubating with guanosine (Guo) to minimize PNP activity while investigating the metabolism of [14C] deoxyguanosine (dGuo) at physiologic concentrations (10 microM) by unstimulated thymocytes, tonsil-derived T and B lymphocytes, and peripheral blood cells over short time periods. Guanosine 107-116 purine nucleoside phosphorylase Homo sapiens 69-72 2104895-2 1990 This study was designed to simulate purine nucleoside phosphorylase (PNP) deficiency by preincubating with guanosine (Guo) to minimize PNP activity while investigating the metabolism of [14C] deoxyguanosine (dGuo) at physiologic concentrations (10 microM) by unstimulated thymocytes, tonsil-derived T and B lymphocytes, and peripheral blood cells over short time periods. Guanosine 118-121 purine nucleoside phosphorylase Homo sapiens 69-72