PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20939743-5 2010 AREAS COVERED IN THIS REVIEW: Preclinical and clinical studies of avanafil, a new oral PDE5 inhibitor being investigated for the treatment of ED. avanafil 66-74 phosphodiesterase 5A Homo sapiens 87-91 20939743-8 2010 TAKE HOME MESSAGE: We propose that avanafil, which displays enhanced selectivity, faster onset of action, and a favorable side-effect profile relative to currently available PDE5 inhibitors, may offer an alternative first line treatment option for men with ED. avanafil 35-43 phosphodiesterase 5A Homo sapiens 174-178