PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2090199-1 1990 We have shown that macrophage-derived prostaglandin (PG)E2 inactivates all interleukin 2 (IL-2) dependent killer cell lineages in the tumor-bearing host, so that chronic indomethacin therapy (CIT) combined with multiple rounds of IL-2 can cure experimental and spontaneous metastases of a variety of murine tumors. Indomethacin 170-182 interleukin 2 Mus musculus 90-94 2090199-1 1990 We have shown that macrophage-derived prostaglandin (PG)E2 inactivates all interleukin 2 (IL-2) dependent killer cell lineages in the tumor-bearing host, so that chronic indomethacin therapy (CIT) combined with multiple rounds of IL-2 can cure experimental and spontaneous metastases of a variety of murine tumors. Indomethacin 170-182 interleukin 2 Mus musculus 230-234