PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20886344-0	2011	Aspirin promotes apoptosis in a murine model of colorectal cancer by mechanisms involving downregulation of IL-6-STAT3 signaling pathway.	Aspirin	0-7	interleukin 6	Mus musculus	108-112	
20886344-1	2011	BACKGROUND AND AIMS: Aspirin is associated with a reduced risk of colorectal cancer (CRC), and it showed inhibited effects on interleukin 6 (IL-6)/signal transducer and activator of transcription 3 (STAT3) signaling pathway which is thought to play an important role in intestinal inflammation and the tumorigenesis of CRC.	Aspirin	21-28	interleukin 6	Mus musculus	126-139	
20886344-1	2011	BACKGROUND AND AIMS: Aspirin is associated with a reduced risk of colorectal cancer (CRC), and it showed inhibited effects on interleukin 6 (IL-6)/signal transducer and activator of transcription 3 (STAT3) signaling pathway which is thought to play an important role in intestinal inflammation and the tumorigenesis of CRC.	Aspirin	21-28	interleukin 6	Mus musculus	141-145	
20886344-6	2011	The expression level of IL-6, which is an upstream molecule of STAT3 and capable of activating STAT3, was reduced in aspirin-treated mice.	Aspirin	117-124	interleukin 6	Mus musculus	24-28	
20886344-8	2011	CONCLUSIONS: Our data suggested that the protective mechanisms of aspirin in CRC may be associated with its effects on induction of CRC cell apoptosis and suppression of IL-6-STAT3 signaling pathway, which implied that aspirin has a potential therapeutic activity in CRC.	Aspirin	66-73	interleukin 6	Mus musculus	170-174	
20886344-8	2011	CONCLUSIONS: Our data suggested that the protective mechanisms of aspirin in CRC may be associated with its effects on induction of CRC cell apoptosis and suppression of IL-6-STAT3 signaling pathway, which implied that aspirin has a potential therapeutic activity in CRC.	Aspirin	219-226	interleukin 6	Mus musculus	170-174