PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20686830-2 2011 Kakkalide and irisolidone down-regulated the gene expression of cytokines [tumor necrosis factor alpha (TNF-alpha) and interleukin-1 beta (IL-1beta)] and cyclooxygenase-2 (COX-2) and the production of pro-inflammatory cytokines, TNF-alpha and IL-1beta, and inflammatory mediators, NO and prostaglandin E(2) (PGE(2)), in LPS-stimulated peritoneal macrophages. kakkalide 0-9 interleukin 1 beta Mus musculus 119-137 20686830-2 2011 Kakkalide and irisolidone down-regulated the gene expression of cytokines [tumor necrosis factor alpha (TNF-alpha) and interleukin-1 beta (IL-1beta)] and cyclooxygenase-2 (COX-2) and the production of pro-inflammatory cytokines, TNF-alpha and IL-1beta, and inflammatory mediators, NO and prostaglandin E(2) (PGE(2)), in LPS-stimulated peritoneal macrophages. kakkalide 0-9 interleukin 1 beta Mus musculus 139-147 20686830-2 2011 Kakkalide and irisolidone down-regulated the gene expression of cytokines [tumor necrosis factor alpha (TNF-alpha) and interleukin-1 beta (IL-1beta)] and cyclooxygenase-2 (COX-2) and the production of pro-inflammatory cytokines, TNF-alpha and IL-1beta, and inflammatory mediators, NO and prostaglandin E(2) (PGE(2)), in LPS-stimulated peritoneal macrophages. kakkalide 0-9 interleukin 1 beta Mus musculus 243-251