PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20683769-3	2011	Therefore, this study aimed to investigate the regulation and function of MMP-2 and its major activator membrane type 1-matrix metalloproteinase (MT1-MMP) as well its inhibitor TIMP-1 in SN under conditions of HFES.	hfes	210-214	matrix metallopeptidase 2	Rattus norvegicus	74-79	
20683769-6	2011	HFES increased MMP-2 and MT1-MMP mRNA and protein expression, whereas TIMP-1 expression remained unchanged.	hfes	0-4	matrix metallopeptidase 2	Rattus norvegicus	15-20	
20683769-6	2011	HFES increased MMP-2 and MT1-MMP mRNA and protein expression, whereas TIMP-1 expression remained unchanged.	hfes	0-4	matrix metallopeptidase 14	Rattus norvegicus	25-32	
20683769-7	2011	Under conditions of HFES, we observed a shift from pro- to active-MMP-2 indicating an increase in MMP-2 enzyme activity.	hfes	20-24	matrix metallopeptidase 2	Rattus norvegicus	66-71	
20683769-7	2011	Under conditions of HFES, we observed a shift from pro- to active-MMP-2 indicating an increase in MMP-2 enzyme activity.	hfes	20-24	matrix metallopeptidase 2	Rattus norvegicus	98-103	
20683769-8	2011	Specific pharmacological MMP-2 inhibition contributed to an increase in pro-NGF amount in the cell culture supernatant and significantly reduced HFES-induced neurite outgrowth.	hfes	145-149	matrix metallopeptidase 2	Rattus norvegicus	25-30	
20683769-9	2011	Losartan abolished HFES-induced nerve sprouting in a significant manner by preventing HFES-induced NGF, MMP-2, and MT1-MMP up-regulation.	Losartan	0-8	matrix metallopeptidase 2	Rattus norvegicus	104-109	
20683769-9	2011	Losartan abolished HFES-induced nerve sprouting in a significant manner by preventing HFES-induced NGF, MMP-2, and MT1-MMP up-regulation.	Losartan	0-8	matrix metallopeptidase 14	Rattus norvegicus	115-122	
20683769-9	2011	Losartan abolished HFES-induced nerve sprouting in a significant manner by preventing HFES-induced NGF, MMP-2, and MT1-MMP up-regulation.	hfes	19-23	matrix metallopeptidase 2	Rattus norvegicus	104-109	
20683769-9	2011	Losartan abolished HFES-induced nerve sprouting in a significant manner by preventing HFES-induced NGF, MMP-2, and MT1-MMP up-regulation.	hfes	19-23	matrix metallopeptidase 14	Rattus norvegicus	115-122	
20683769-9	2011	Losartan abolished HFES-induced nerve sprouting in a significant manner by preventing HFES-induced NGF, MMP-2, and MT1-MMP up-regulation.	hfes	86-90	matrix metallopeptidase 2	Rattus norvegicus	104-109	
20683769-9	2011	Losartan abolished HFES-induced nerve sprouting in a significant manner by preventing HFES-induced NGF, MMP-2, and MT1-MMP up-regulation.	hfes	86-90	matrix metallopeptidase 14	Rattus norvegicus	115-122