PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2065327-0 1991 Correlations between polyamine analogue-induced increases in spermidine/spermine N1-acetyltransferase activity, polyamine pool depletion, and growth inhibition in human melanoma cell lines. Polyamines 21-30 spermidine/spermine N1-acetyltransferase 1 Homo sapiens 61-101 2065327-4 1991 In MALME-3 cells, SSAT accumulation was found to be differentially modulated by the BESPM homologues, N1,N11-bis-(ethyl)norspermine and N1,N14-bis-(ethyl)homospermine, which were 5-fold more and 9-fold less effective, respectively, than BESPM in increasing SSAT but similar in analogue uptake and effects on polyamine biosynthesis and cell growth inhibition. Polyamines 308-317 spermidine/spermine N1-acetyltransferase 1 Homo sapiens 18-22 2065327-6 1991 The relationship between SSAT induction and growth sensitivity was deduced to be a possible function of increased excretion of acetylated polyamines leading to enhanced polyamine pool depletion. Polyamines 138-148 spermidine/spermine N1-acetyltransferase 1 Homo sapiens 25-29 2065327-6 1991 The relationship between SSAT induction and growth sensitivity was deduced to be a possible function of increased excretion of acetylated polyamines leading to enhanced polyamine pool depletion. Polyamines 138-147 spermidine/spermine N1-acetyltransferase 1 Homo sapiens 25-29