PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2061301-0	1991	T-cell antigen receptor ligation induces tyrosine phosphorylation of phospholipase C-gamma 1.	Tyrosine	41-49	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	0-23	
2061301-2	1991	Although the mechanism by which TCR ligation regulates PLC activity is unknown, recent studies suggest that coupling of this receptor complex to PLC activity is dependent on an intermediate protein tyrosine phosphorylation event(s).	Tyrosine	198-206	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	32-35	
2061301-3	1991	In the present study, we demonstrate that antibody-mediated TCR cross-linkage results in the tyrosine phosphorylation of PLC-gamma 1.	Tyrosine	93-101	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	60-63	
2061301-4	1991	Stimulation of the TCR for 30 s induced a 4-5-fold increase in the level of PLC activity recovered in anti-phosphotyrosine (Tyr(P)) antibody immunoprecipitates from stimulated Jurkat cells.	Tyrosine	124-127	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	19-22	
2061301-6	1991	Furthermore, the TCR-mediated increase in anti-Tyr(P) antibody-bound PLC activity was inhibited by staurosporine at drug concentrations identical with those required for in vivo inhibition of TCR-dependent phosphoinositide breakdown.	Tyrosine	47-50	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	17-20	
2061301-6	1991	Furthermore, the TCR-mediated increase in anti-Tyr(P) antibody-bound PLC activity was inhibited by staurosporine at drug concentrations identical with those required for in vivo inhibition of TCR-dependent phosphoinositide breakdown.	Tyrosine	47-50	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	192-195	
2061301-7	1991	Immunoblot analyses demonstrated that TCR ligation dramatically increased the level of tyrosine-phosphorylated PLC-gamma 1 present in anti-Tyr(P) antibody immunoprecipitates from stimulated Jurkat cells.	Tyrosine	87-95	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	38-41	
2061301-7	1991	Immunoblot analyses demonstrated that TCR ligation dramatically increased the level of tyrosine-phosphorylated PLC-gamma 1 present in anti-Tyr(P) antibody immunoprecipitates from stimulated Jurkat cells.	Tyrosine	139-142	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	38-41	
2061301-8	1991	These results strongly suggest that the TCR complex expressed by Jurkat cells is functionally coupled to the phosphoinositide-dependent signaling pathway through the tyrosine phosphorylation of PLC-gamma 1.	Tyrosine	166-174	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	40-43