PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20607587-0	2011	Modulation of P-gp expression by lapatinib.	Lapatinib	33-42	ATP binding cassette subfamily B member 1	Homo sapiens	14-18	
20607587-4	2011	We examined the impact of co-incubation of chemotherapy drugs in combination with lapatinib in P-gp over-expressing drug resistant cells.	Lapatinib	82-91	ATP binding cassette subfamily B member 1	Homo sapiens	95-99	
20607587-5	2011	Unexpectedly, lapatinib treatment, at clinically relevant concentrations, increased levels of the P-gp drug transporter in a dose- and time-responsive manner.	Lapatinib	14-23	ATP binding cassette subfamily B member 1	Homo sapiens	98-102	
20607587-7	2011	Despite the lapatinib-induced alteration in P-gp expression, use of accumulation, efflux and toxicity assays demonstrated that the induced alteration in P-gp expression by lapatinib had little direct impact on drug resistance.	Lapatinib	12-21	ATP binding cassette subfamily B member 1	Homo sapiens	44-48	
20607587-7	2011	Despite the lapatinib-induced alteration in P-gp expression, use of accumulation, efflux and toxicity assays demonstrated that the induced alteration in P-gp expression by lapatinib had little direct impact on drug resistance.	Lapatinib	172-181	ATP binding cassette subfamily B member 1	Homo sapiens	153-157