PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20570635-0 2010 Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity. Oxysterols 88-97 ATP binding cassette subfamily G member 1 Homo sapiens 20-25 20570635-7 2010 Trophoblasts transfected with ABCA1 or ABCG1 siRNA were more sensitive to toxic oxysterols substrates (25-hydroxycholesterol and 7-ketocholesterol) compared to mock-transfected cells, while prior treatment with T0901317 reduced oxysterol-mediated toxicity. Oxysterols 80-90 ATP binding cassette subfamily G member 1 Homo sapiens 39-44 20570635-7 2010 Trophoblasts transfected with ABCA1 or ABCG1 siRNA were more sensitive to toxic oxysterols substrates (25-hydroxycholesterol and 7-ketocholesterol) compared to mock-transfected cells, while prior treatment with T0901317 reduced oxysterol-mediated toxicity. Oxysterols 80-89 ATP binding cassette subfamily G member 1 Homo sapiens 39-44 20570635-8 2010 These results identify syncytial ABCA1 and ABCG1 as important, inducible cholesterol transporters which also prevent placental accumulation of cytotoxic oxysterols. Oxysterols 153-163 ATP binding cassette subfamily G member 1 Homo sapiens 43-48