PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20410134-1	2010	Aldosterone-induced increases in apical membrane epithelial sodium channel (ENaC) density and Na transport involve the induction of 14-3-3 protein expression and their association with Nedd4-2, a substrate of serum- and glucocorticoid-induced kinase (SGK1)-mediated phosphorylation.	Aldosterone	0-11	NEDD4 like E3 ubiquitin protein ligase	Homo sapiens	185-192	
20410134-1	2010	Aldosterone-induced increases in apical membrane epithelial sodium channel (ENaC) density and Na transport involve the induction of 14-3-3 protein expression and their association with Nedd4-2, a substrate of serum- and glucocorticoid-induced kinase (SGK1)-mediated phosphorylation.	Aldosterone	0-11	serum/glucocorticoid regulated kinase 1	Homo sapiens	251-255	
20410134-2	2010	A search for other 14-3-3 binding proteins in aldosterone-treated cortical collecting duct (CCD) cells identified the Rab-GAP, AS160, an Akt/PKB substrate whose phosphorylation contributes to the recruitment of GLUT4 transporters to adipocyte plasma membranes in response to insulin.	Aldosterone	46-57	ArfGAP with FG repeats 1	Homo sapiens	118-121	
20410134-2	2010	A search for other 14-3-3 binding proteins in aldosterone-treated cortical collecting duct (CCD) cells identified the Rab-GAP, AS160, an Akt/PKB substrate whose phosphorylation contributes to the recruitment of GLUT4 transporters to adipocyte plasma membranes in response to insulin.	Aldosterone	46-57	TBC1 domain family member 4	Homo sapiens	127-132	
20410134-2	2010	A search for other 14-3-3 binding proteins in aldosterone-treated cortical collecting duct (CCD) cells identified the Rab-GAP, AS160, an Akt/PKB substrate whose phosphorylation contributes to the recruitment of GLUT4 transporters to adipocyte plasma membranes in response to insulin.	Aldosterone	46-57	solute carrier family 2 member 4	Homo sapiens	211-216	
20410134-5	2010	In AS160 overexpressing epithelia, however, aldosterone increased apical ENaC and I(sc) 2.5-fold relative to aldosterone alone, thus recruiting the accumulated ENaC to the apical membrane.	Aldosterone	44-55	TBC1 domain family member 4	Homo sapiens	3-8	
20410134-6	2010	Conversely, AS160 knockdown increased apical membrane ENaC and I(sc) under basal conditions to approximately 80% of aldosterone-stimulated values, attenuating further steroid effects.	Aldosterone	116-127	TBC1 domain family member 4	Homo sapiens	12-17	
20410134-6	2010	Conversely, AS160 knockdown increased apical membrane ENaC and I(sc) under basal conditions to approximately 80% of aldosterone-stimulated values, attenuating further steroid effects.	Steroids	167-174	TBC1 domain family member 4	Homo sapiens	12-17	
20410134-7	2010	Aldosterone induced AS160 phosphorylation at five sites, predominantly at the SGK1 sites T568 and S751, and evoked AS160 binding to the steroid-induced 14-3-3 isoforms, beta and epsilon.	Aldosterone	0-11	TBC1 domain family member 4	Homo sapiens	20-25	
20410134-7	2010	Aldosterone induced AS160 phosphorylation at five sites, predominantly at the SGK1 sites T568 and S751, and evoked AS160 binding to the steroid-induced 14-3-3 isoforms, beta and epsilon.	Aldosterone	0-11	serum/glucocorticoid regulated kinase 1	Homo sapiens	78-82	
20410134-7	2010	Aldosterone induced AS160 phosphorylation at five sites, predominantly at the SGK1 sites T568 and S751, and evoked AS160 binding to the steroid-induced 14-3-3 isoforms, beta and epsilon.	Aldosterone	0-11	TBC1 domain family member 4	Homo sapiens	115-120	
20410134-7	2010	Aldosterone induced AS160 phosphorylation at five sites, predominantly at the SGK1 sites T568 and S751, and evoked AS160 binding to the steroid-induced 14-3-3 isoforms, beta and epsilon.	Steroids	136-143	TBC1 domain family member 4	Homo sapiens	20-25	
20410134-7	2010	Aldosterone induced AS160 phosphorylation at five sites, predominantly at the SGK1 sites T568 and S751, and evoked AS160 binding to the steroid-induced 14-3-3 isoforms, beta and epsilon.	Steroids	136-143	TBC1 domain family member 4	Homo sapiens	115-120	
20410134-8	2010	AS160 mutations at SGK1 phospho-sites blocked its selective interaction with 14-3-3beta and epsilon and suppressed the ability of expressed AS160 to augment aldosterone action.	Aldosterone	157-168	TBC1 domain family member 4	Homo sapiens	0-5	
20410134-8	2010	AS160 mutations at SGK1 phospho-sites blocked its selective interaction with 14-3-3beta and epsilon and suppressed the ability of expressed AS160 to augment aldosterone action.	Aldosterone	157-168	serum/glucocorticoid regulated kinase 1	Homo sapiens	19-23	
20410134-8	2010	AS160 mutations at SGK1 phospho-sites blocked its selective interaction with 14-3-3beta and epsilon and suppressed the ability of expressed AS160 to augment aldosterone action.	Aldosterone	157-168	TBC1 domain family member 4	Homo sapiens	140-145