PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20351197-3 2010 In response to both 17beta-estradiol (E2) and the xenoestrogen diethylstilbestrol, ER signaling via phosphatidylinositol 3-kinase/protein kinase B phosphorylates EZH2 at S21, reducing levels of trimethylation of lysine 27 on histone H3 in hormone-responsive cells. Lysine 212-218 estrogen receptor 1 Homo sapiens 83-85 20351197-4 2010 During windows of uterine development that are susceptible to developmental reprogramming, activation of this ER signaling pathway by diethylstilbestrol resulted in phosphorylation of EZH2 and reduced levels of trimethylation of lysine 27 on histone H3 in chromatin of the developing uterus. Lysine 229-235 estrogen receptor 1 Homo sapiens 110-112