PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20348231-4	2010	The overarching conceptual framework guiding experimentation is that TCDD disrupts plasmacytic differentiation by altering the expression or activity for upstream regulators of Blimp-1.	Polychlorinated Dibenzodioxins	69-73	PR domain containing 1, with ZNF domain	Mus musculus	177-184	
20348231-6	2010	TCDD significantly impaired LPS-activated expression of major histocompatibility complex class II, cluster of differentiation (CD)69, CD80, and CD86.	Polychlorinated Dibenzodioxins	0-4	CD80 antigen	Mus musculus	134-138	
20348231-6	2010	TCDD significantly impaired LPS-activated expression of major histocompatibility complex class II, cluster of differentiation (CD)69, CD80, and CD86.	Polychlorinated Dibenzodioxins	0-4	CD86 antigen	Mus musculus	144-148	
20348231-7	2010	Immunosuppressive concentrations of TCDD also suppressed LPS-activated Blimp-1 and phosphorylated c-Jun expression, whereas elevating BCL-6 expression.	Polychlorinated Dibenzodioxins	36-40	PR domain containing 1, with ZNF domain	Mus musculus	71-78	
20348231-7	2010	Immunosuppressive concentrations of TCDD also suppressed LPS-activated Blimp-1 and phosphorylated c-Jun expression, whereas elevating BCL-6 expression.	Polychlorinated Dibenzodioxins	36-40	jun proto-oncogene	Mus musculus	98-103	
20348231-7	2010	Immunosuppressive concentrations of TCDD also suppressed LPS-activated Blimp-1 and phosphorylated c-Jun expression, whereas elevating BCL-6 expression.	Polychlorinated Dibenzodioxins	36-40	B cell leukemia/lymphoma 6	Mus musculus	134-139	
20348231-8	2010	Because BCL-6 and c-Jun are directly and indirectly regulated by the kinases AKT, extracellular signal-regulated kinase (ERK), and Jun N-terminal kinase (JNK), it was hypothesized that TCDD alters toll-like receptor-activated kinase phosphorylation.	Polychlorinated Dibenzodioxins	185-189	B cell leukemia/lymphoma 6	Mus musculus	8-13	
20348231-8	2010	Because BCL-6 and c-Jun are directly and indirectly regulated by the kinases AKT, extracellular signal-regulated kinase (ERK), and Jun N-terminal kinase (JNK), it was hypothesized that TCDD alters toll-like receptor-activated kinase phosphorylation.	Polychlorinated Dibenzodioxins	185-189	jun proto-oncogene	Mus musculus	18-23	
20348231-8	2010	Because BCL-6 and c-Jun are directly and indirectly regulated by the kinases AKT, extracellular signal-regulated kinase (ERK), and Jun N-terminal kinase (JNK), it was hypothesized that TCDD alters toll-like receptor-activated kinase phosphorylation.	Polychlorinated Dibenzodioxins	185-189	thymoma viral proto-oncogene 1	Mus musculus	77-80	
20348231-8	2010	Because BCL-6 and c-Jun are directly and indirectly regulated by the kinases AKT, extracellular signal-regulated kinase (ERK), and Jun N-terminal kinase (JNK), it was hypothesized that TCDD alters toll-like receptor-activated kinase phosphorylation.	Polychlorinated Dibenzodioxins	185-189	mitogen-activated protein kinase 1	Mus musculus	82-119	
20348231-8	2010	Because BCL-6 and c-Jun are directly and indirectly regulated by the kinases AKT, extracellular signal-regulated kinase (ERK), and Jun N-terminal kinase (JNK), it was hypothesized that TCDD alters toll-like receptor-activated kinase phosphorylation.	Polychlorinated Dibenzodioxins	185-189	mitogen-activated protein kinase 1	Mus musculus	121-124	
20348231-8	2010	Because BCL-6 and c-Jun are directly and indirectly regulated by the kinases AKT, extracellular signal-regulated kinase (ERK), and Jun N-terminal kinase (JNK), it was hypothesized that TCDD alters toll-like receptor-activated kinase phosphorylation.	Polychlorinated Dibenzodioxins	185-189	mitogen-activated protein kinase 8	Mus musculus	131-152	
20348231-8	2010	Because BCL-6 and c-Jun are directly and indirectly regulated by the kinases AKT, extracellular signal-regulated kinase (ERK), and Jun N-terminal kinase (JNK), it was hypothesized that TCDD alters toll-like receptor-activated kinase phosphorylation.	Polychlorinated Dibenzodioxins	185-189	mitogen-activated protein kinase 8	Mus musculus	154-157	
20348231-9	2010	TCDD at 0.03 and 0.3 nM significantly impaired phosphorylation of AKT, ERK, and JNK in CH12.LX B cells activated with LPS, CpG oligonucleotides, or resiquimod (R848).	Polychlorinated Dibenzodioxins	0-4	thymoma viral proto-oncogene 1	Mus musculus	66-69	
20348231-9	2010	TCDD at 0.03 and 0.3 nM significantly impaired phosphorylation of AKT, ERK, and JNK in CH12.LX B cells activated with LPS, CpG oligonucleotides, or resiquimod (R848).	Polychlorinated Dibenzodioxins	0-4	mitogen-activated protein kinase 1	Mus musculus	71-74	
20348231-9	2010	TCDD at 0.03 and 0.3 nM significantly impaired phosphorylation of AKT, ERK, and JNK in CH12.LX B cells activated with LPS, CpG oligonucleotides, or resiquimod (R848).	Polychlorinated Dibenzodioxins	0-4	mitogen-activated protein kinase 8	Mus musculus	80-83	
20348231-9	2010	TCDD at 0.03 and 0.3 nM significantly impaired phosphorylation of AKT, ERK, and JNK in CH12.LX B cells activated with LPS, CpG oligonucleotides, or resiquimod (R848).	CPG-oligonucleotide	123-143	thymoma viral proto-oncogene 1	Mus musculus	66-69	
20348231-10	2010	In primary B cells, R848-activated phosphorylation of AKT, ERK, and JNK was also impaired by TCDD at 30 nM.	Polychlorinated Dibenzodioxins	93-97	thymoma viral proto-oncogene 1	Mus musculus	54-57	
20348231-10	2010	In primary B cells, R848-activated phosphorylation of AKT, ERK, and JNK was also impaired by TCDD at 30 nM.	Polychlorinated Dibenzodioxins	93-97	mitogen-activated protein kinase 8	Mus musculus	68-71