PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20307623-0	2010	Exposure of human skin to benzo[a]pyrene: role of CYP1A1 and aryl hydrocarbon receptor in oxidative stress generation.	Benzo(a)pyrene	26-40	aryl hydrocarbon receptor	Homo sapiens	61-86	
20307623-2	2010	BaP is known to bind with high specificity to the aryl hydrocarbon receptor (AhR), modifying the expression of CYP1A1, involved both in cancer and inflammation.	Benzo(a)pyrene	0-3	aryl hydrocarbon receptor	Homo sapiens	50-75	
20307623-2	2010	BaP is known to bind with high specificity to the aryl hydrocarbon receptor (AhR), modifying the expression of CYP1A1, involved both in cancer and inflammation.	Benzo(a)pyrene	0-3	aryl hydrocarbon receptor	Homo sapiens	77-80	
20307623-4	2010	AhR and CYP1A1 expression was evaluated by Western blotting, which revealed their presence even in control untreated skin; both enzyme and receptor increased more than twofold after exposure to BaP.	Benzo(a)pyrene	194-197	aryl hydrocarbon receptor	Homo sapiens	0-3	
20307623-8	2010	The results of this experiment indicate that BaP, an AhR agonist, can significantly increase receptor and CYP1A1 expression and induce oxidative stress in human skin, confirming the involvement of this pathway in the pathogenesis of tissue damage due to polycyclic aromatic hydrocarbons.	Benzo(a)pyrene	45-48	aryl hydrocarbon receptor	Homo sapiens	53-56