PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20215810-6 2010 CONCLUSION: Both isomers of metoprolol upregulate connexin-43 in cultured cardiomyocytes by a beta-adrenoceptor-independent mechanism. Metoprolol 28-38 gap junction protein, alpha 1 Rattus norvegicus 50-61 20215810-7 2010 Since the enhanced presence of connexin-43 in cell membranes under metoprolol was not accompanied by enhanced connexin-43 mRNA, we assume that the metoprolol effect involves reduced connexin-43 degradation. Metoprolol 67-77 gap junction protein, alpha 1 Rattus norvegicus 31-42 20215810-7 2010 Since the enhanced presence of connexin-43 in cell membranes under metoprolol was not accompanied by enhanced connexin-43 mRNA, we assume that the metoprolol effect involves reduced connexin-43 degradation. Metoprolol 147-157 gap junction protein, alpha 1 Rattus norvegicus 31-42