PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20159823-0 2010 Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate. Abiraterone Acetate 126-145 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 110-115 20159823-1 2010 PURPOSE: The principal objective of this trial was to evaluate the antitumor activity of abiraterone acetate, an oral, specific, irreversible inhibitor of CYP17 in docetaxel-treated patients with castration-resistant prostate cancer (CRPC). Abiraterone Acetate 89-108 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 155-160