PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20113171-1 2010 Lipid nano-emulsions (LNEs) having a mean droplet size of approximately 50 nm were investigated as drug carriers for paclitaxel (TXL) to achieve its satisfactory loadings and to develop a pharmaceutically acceptable alternative to the current formulation, Taxol. lnes 22-26 thioredoxin like 1 Homo sapiens 129-132 20113171-1 2010 Lipid nano-emulsions (LNEs) having a mean droplet size of approximately 50 nm were investigated as drug carriers for paclitaxel (TXL) to achieve its satisfactory loadings and to develop a pharmaceutically acceptable alternative to the current formulation, Taxol. Paclitaxel 117-127 thioredoxin like 1 Homo sapiens 129-132 20113171-2 2010 TXL was incorporated into the LNEs at 2.0 mg/ml without changes in particle size or drug precipitation. lnes 30-34 thioredoxin like 1 Homo sapiens 0-3 20113171-3 2010 In the cytotoxicity study, TXL-loaded LNEs had cytotoxicity to HeLa cells equivalent to that of TXL alone; the 50% growth inhibitory concentrations (IC(50)) of TXL-loaded LNEs and TXL alone were 1.53 +/- 0.23 nM and 1.76 +/- 0.08 nM, respectively. lnes 38-42 thioredoxin like 1 Homo sapiens 27-30 20113171-3 2010 In the cytotoxicity study, TXL-loaded LNEs had cytotoxicity to HeLa cells equivalent to that of TXL alone; the 50% growth inhibitory concentrations (IC(50)) of TXL-loaded LNEs and TXL alone were 1.53 +/- 0.23 nM and 1.76 +/- 0.08 nM, respectively. lnes 171-175 thioredoxin like 1 Homo sapiens 27-30