PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20053791-0	2010	CREB trans-activation of disruptor of telomeric silencing-1 mediates forskolin inhibition of CTGF transcription in mesangial cells.	Colforsin	69-78	cAMP responsive element binding protein 1	Homo sapiens	0-4	
20053791-0	2010	CREB trans-activation of disruptor of telomeric silencing-1 mediates forskolin inhibition of CTGF transcription in mesangial cells.	Colforsin	69-78	cellular communication network factor 2	Homo sapiens	93-97	
20053791-2	2010	The adenylyl cyclase agonist forskolin inhibits CTGF expression in mesangial cells by unclear mechanisms.	Colforsin	29-38	cellular communication network factor 2	Homo sapiens	48-52	
20053791-4	2010	In the present study, we characterized the involvement of Dot1 in mediating the inhibitory effect of forskolin on CTGF transcription in mouse mesangial cells.	Colforsin	101-110	cellular communication network factor 2	Mus musculus	114-118	
20053791-5	2010	Overexpression of Dot1 or treatment with forskolin dramatically suppressed basal CTGF mRNA levels and CTGF promoter-luciferase activity, while hypermethylating H3K79 in chromatin associated with the CTGF promoter.	Colforsin	41-50	cellular communication network factor 2	Homo sapiens	81-85	
20053791-5	2010	Overexpression of Dot1 or treatment with forskolin dramatically suppressed basal CTGF mRNA levels and CTGF promoter-luciferase activity, while hypermethylating H3K79 in chromatin associated with the CTGF promoter.	Colforsin	41-50	cellular communication network factor 2	Homo sapiens	102-106	
20053791-5	2010	Overexpression of Dot1 or treatment with forskolin dramatically suppressed basal CTGF mRNA levels and CTGF promoter-luciferase activity, while hypermethylating H3K79 in chromatin associated with the CTGF promoter.	Colforsin	41-50	cellular communication network factor 2	Homo sapiens	102-106	
20053791-6	2010	siRNA knockdown of Dot1 abrogated the inhibitory effect of forskolin on CTGF mRNA expression.	Colforsin	59-68	cellular communication network factor 2	Homo sapiens	72-76	
20053791-8	2010	Overexpression of CREB enhanced forskolin-stimulated Dot1 promoter activity.	Colforsin	32-41	cAMP responsive element binding protein 1	Homo sapiens	18-22	
20053791-12	2010	We conclude that forskolin stimulates CREB-mediated trans-activation of the Dot1 gene, which leads to hypermethylation of histone H3K79 at the CTGF promoter, and inhibition of CTGF transcription.	Colforsin	17-26	cAMP responsive element binding protein 1	Homo sapiens	38-42	
20053791-12	2010	We conclude that forskolin stimulates CREB-mediated trans-activation of the Dot1 gene, which leads to hypermethylation of histone H3K79 at the CTGF promoter, and inhibition of CTGF transcription.	Colforsin	17-26	cellular communication network factor 2	Homo sapiens	143-147	
20053791-12	2010	We conclude that forskolin stimulates CREB-mediated trans-activation of the Dot1 gene, which leads to hypermethylation of histone H3K79 at the CTGF promoter, and inhibition of CTGF transcription.	Colforsin	17-26	cellular communication network factor 2	Homo sapiens	176-180