PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20036247-2 2010 Since high glucose has been shown to increase growth factor receptor activation, we investigated the role of epidermal growth factor receptor (EGF-R) and platelet-derived growth factor receptor (PDGF-R) transactivation in high glucose-induced enhanced expression of Gq/11alpha and PLCbeta. Glucose 227-234 epidermal growth factor receptor Homo sapiens 109-141 20036247-3 2010 Pre-treatment of A10 VSMC with high glucose (26 mM) for 3 days, increased the levels of Gqalpha, G11alpha, PLCbeta-1 and PLCbeta-2 proteins which were restored to control levels by AG1478, an inhibitor of EGF-R, AG1295, an inhibitor of PDGF-R and PP2, an inhibitor of c-Src but not by PP3. Glucose 36-43 epidermal growth factor receptor Homo sapiens 205-210 20036247-5 2010 High glucose also increased the phosphorylation of EGF-R and PDGF-R which was abolished by AG1478, AG1295 and PP2. Glucose 5-12 epidermal growth factor receptor Homo sapiens 51-56