PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20032300-4 2010 Furthermore, adding synthetic Abeta peptide, the pathogenic product of APP, to cultured cells causes rapid and robust chromosome mis-segregation leading to aneuploid, including trisomy 21, daughters, which is prevented by LiCl addition or Ca(2+) chelation and is replicated in tau KO cells, implicating GSK-3beta, calpain, and Tau-dependent microtubule transport in the aneugenic activity of Abeta. Lithium Chloride 222-226 glycogen synthase kinase 3 alpha Homo sapiens 303-312