PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20023768-7 2009 The MH-triggering volatile anesthetic, halothane, activates RyR1(R615C) and RyR1(WT) to a similar extent, using [(3)H]ryanodine binding as a measure of activation. Halothane 39-48 ryanodine receptor 1 Homo sapiens 60-64 20023768-7 2009 The MH-triggering volatile anesthetic, halothane, activates RyR1(R615C) and RyR1(WT) to a similar extent, using [(3)H]ryanodine binding as a measure of activation. Halothane 39-48 ryanodine receptor 1 Homo sapiens 76-80 20023768-8 2009 Modeling RyR1 array function with parameters modified to simulate the loss of functional inter-RyR coupling recapitulates the MH molecular phenotype-RyR1 channels leaky to Ca(2+) at rest and long open-times following exposure to halothane. Halothane 229-238 ryanodine receptor 1 Homo sapiens 9-13 20023768-8 2009 Modeling RyR1 array function with parameters modified to simulate the loss of functional inter-RyR coupling recapitulates the MH molecular phenotype-RyR1 channels leaky to Ca(2+) at rest and long open-times following exposure to halothane. Halothane 229-238 ryanodine receptor 1 Homo sapiens 9-12 20023768-8 2009 Modeling RyR1 array function with parameters modified to simulate the loss of functional inter-RyR coupling recapitulates the MH molecular phenotype-RyR1 channels leaky to Ca(2+) at rest and long open-times following exposure to halothane. Halothane 229-238 ryanodine receptor 1 Homo sapiens 149-153