PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20007733-1 2010 BACKGROUND: A previous study from our laboratories showed that a significant reduction in spinal N-methyl-D-aspartate (NMDA) receptor NR1 subunit phosphorylation (pNR1) is associated with the antiallodynic effect produced by intrathecal (IT) injection of the alpha-2 adrenoceptor agonist, clonidine, in neuropathic rats. Clonidine 289-298 glutamate ionotropic receptor NMDA type subunit 1 Rattus norvegicus 134-137 20007733-10 2010 Furthermore, these findings suggest that the modulation of spinal NR1 phosphorylation is linked to the effect of IT clonidine on postsynaptic neuronal activity. Clonidine 116-125 glutamate ionotropic receptor NMDA type subunit 1 Rattus norvegicus 66-69