PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19960413-0	2010	Inhibitory effects of deoxypodophyllotoxin from Anthriscus sylvestris on human CYP2C9 and CYP3A4.	deoxypodophyllotoxin	22-42	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	79-85	
19960413-3	2010	When a mixture of specific CYP substrates was incubated with DPT in HLM, CYP2C9-catalyzed diclofenac 4-hydroxylation and CYP3A4-catalyzed midazolam 1-hydroxylation were strongly inhibited by DPT, with IC (50) values of 6.3 and 9.2 microM, respectively.	deoxypodophyllotoxin	61-64	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	73-79	
19960413-3	2010	When a mixture of specific CYP substrates was incubated with DPT in HLM, CYP2C9-catalyzed diclofenac 4-hydroxylation and CYP3A4-catalyzed midazolam 1-hydroxylation were strongly inhibited by DPT, with IC (50) values of 6.3 and 9.2 microM, respectively.	deoxypodophyllotoxin	191-194	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	73-79	
19960413-5	2010	From these results, DPT was characterized to be a competitive inhibitor of CYP2C9 and CYP3A4, with K(i) values of 3.5 and 10.8 microM in HLM and 24.9 and 3.5 microM in baculovirus-insect cell-expressed human CYPs, respectively.	deoxypodophyllotoxin	20-23	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	75-81