PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19880272-0 2010 Aspirin inhibits MMP-9 mRNA expression and release via the PPARalpha/gamma and COX-2/mPGES-1-mediated pathways in macrophages derived from THP-1 cells. Aspirin 0-7 prostaglandin E synthase Mus musculus 85-92 19880272-4 2010 Additionally, the COX-2 mRNA expression, mPGES-1 mRNA and protein expression in macrophages were all decreased after incubation with aspirin for 24h and the PGE(2) release was also decreased. Aspirin 133-140 prostaglandin E synthase Mus musculus 41-48 19880272-7 2010 It might be concluded that aspirin could inhibit the MMP-9 gene expression and release through the PPARalpha/gamma and COX-2/mPGES-1-mediated pathways and the two pathways might be partly overlapped and even be interrelated. Aspirin 27-34 prostaglandin E synthase Mus musculus 125-132