PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19855246-4	2009	: As part of a phase 1 clinical trial, we investigated the effect of CP-690,550 after 29 days of 30 mg twice daily treatment at the cellular level in eight kidney transplant patients by studying ex vivo phosphorylation of STAT5 (P-STAT5), the key substrate of JAK3.	tofacitinib	69-75	signal transducer and activator of transcription 5A	Homo sapiens	229-236	
19855246-8	2009	At the functional level, the inhibitory effect of CP-690,550 was confirmed by determining the expression of several STAT5 targets genes.	tofacitinib	50-56	signal transducer and activator of transcription 5A	Homo sapiens	116-121	
19855246-10	2009	: Analysis of P-STAT5 may, therefore, be used to determine the immunomodulatory effect of CP-690,550 at the cellular level in transplant patients.	tofacitinib	90-96	signal transducer and activator of transcription 5A	Homo sapiens	14-21