PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1981505-0	1990	Quinolone inhibition of cytochrome P-450-dependent caffeine metabolism in human liver microsomes.	Caffeine	51-59	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	24-40	
1981505-7	1990	The results indicate that the reduction of caffeine clearance by concomitant quinolone application observed in vivo is primarily due to a competitive interaction of the inhibiting quinolones with the cytochrome P-450 isoenzyme(s) mediating caffeine demethylation.	Caffeine	43-51	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	200-216	
1981505-7	1990	The results indicate that the reduction of caffeine clearance by concomitant quinolone application observed in vivo is primarily due to a competitive interaction of the inhibiting quinolones with the cytochrome P-450 isoenzyme(s) mediating caffeine demethylation.	Caffeine	240-248	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	200-216