PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19706164-0	2009	Enhanced sensitivity of celecoxib in human glioblastoma cells: Induction of DNA damage leading to p53-dependent G1 cell cycle arrest and autophagy.	Celecoxib	24-33	tumor protein p53	Homo sapiens	98-101	
19706164-6	2009	We investigated whether the anti-glioblastoma responses of celecoxib were p53-dependent, and whether celecoxib induced DNA damage leading to p53-dependent G1 cell cycle arrest, followed by autophagy or apoptosis.	Celecoxib	101-110	tumor protein p53	Homo sapiens	141-144	
19706164-8	2009	Inhibition of functional p53 in glioblastoma cells significantly reduced the anti-proliferative effect of celecoxib.	Celecoxib	106-115	tumor protein p53	Homo sapiens	25-28	
19706164-9	2009	In U87MG cells, celecoxib (8 and 30 muM) significantly induced DNA damage and inhibited DNA synthesis, corresponding with p53 activation.	Celecoxib	16-25	tumor protein p53	Homo sapiens	122-125	
19706164-16	2009	CONCLUSION: Our findings reveal that p53 increases human glioblastoma sensitivity to celecoxib.	Celecoxib	85-94	tumor protein p53	Homo sapiens	37-40	
19706164-17	2009	Celecoxib inhibits glioblastoma cell viability by induction of DNA damage, leading to p53-dependent G1 cell cycle arrest and p53-dependent autophagy, but not apoptosis.	Celecoxib	0-9	tumor protein p53	Homo sapiens	86-89	
19706164-17	2009	Celecoxib inhibits glioblastoma cell viability by induction of DNA damage, leading to p53-dependent G1 cell cycle arrest and p53-dependent autophagy, but not apoptosis.	Celecoxib	0-9	tumor protein p53	Homo sapiens	125-128